diff --git a/package/busybox/busybox.mk b/package/busybox/busybox.mk
index 1fed332764..6e5301f751 100644
--- a/package/busybox/busybox.mk
+++ b/package/busybox/busybox.mk
@@ -40,6 +40,11 @@ $(BUSYBOX_DIR)/.configured: $(BUSYBOX_DIR)/.unpacked $(BUSYBOX_CONFIG_FILE)
 	if [ -f $(BUSYBOX_DIR)/Rules.mak ]; then \
 		$(SED) "s,^CROSS.*,CROSS=$(TARGET_CROSS)\n\
 		PREFIX=$(TARGET_DIR),;" $(BUSYBOX_DIR)/Rules.mak ; \
+	else \
+		$(SED) s,^CONFIG_PREFIX=.*,CONFIG_PREFIX=\"$(TARGET_DIR)\", \
+			$(BUSYBOX_DIR)/.config ; \
+		$(SED) s,^PREFIX=.*,CONFIG_PREFIX=\"$(TARGET_DIR)\", \
+			$(BUSYBOX_DIR)/.config ; \
 	fi
 ifeq ($(BR2_LARGEFILE),y)
 	$(SED) "s/^.*CONFIG_LFS.*/CONFIG_LFS=y/;" $(BUSYBOX_DIR)/.config