diff --git a/libgc/include/private/gcconfig.h b/libgc/include/private/gcconfig.h
index e2bdf13ac3e..f962200ba4e 100644
--- a/libgc/include/private/gcconfig.h
+++ b/libgc/include/private/gcconfig.h
@@ -2255,6 +2255,14 @@
 #   define GETPAGESIZE() getpagesize()
 # endif
 
+#if defined(HOST_ANDROID) && !(__ANDROID_API__ >= 23) \
+    && ((defined(MIPS) && (CPP_WORDSZ == 32)) \
+        || defined(ARM32) || defined(I386) /* but not x32 */)
+  /* tkill() exists only on arm32/mips(32)/x86. */
+  /* NDK r11+ deprecates tkill() but keeps it for Mono clients. */
+# define USE_TKILL_ON_ANDROID
+#endif
+
 # if defined(SUNOS5) || defined(DRSNX) || defined(UTS4)
 	    /* OS has SVR4 generic features.  Probably others also qualify.	*/
 #   define SVR4
diff --git a/libgc/pthread_stop_world.c b/libgc/pthread_stop_world.c
index f93ce26b562..4a49a6d578c 100644
--- a/libgc/pthread_stop_world.c
+++ b/libgc/pthread_stop_world.c
@@ -336,7 +336,7 @@ void GC_push_all_stacks()
 pthread_t GC_stopping_thread;
 int GC_stopping_pid;
 
-#ifdef HOST_ANDROID
+#ifdef USE_TKILL_ON_ANDROID
 static
 int android_thread_kill(pid_t tid, int sig)
 {
diff --git a/mono/metadata/threads.c b/mono/metadata/threads.c
index ad9b8823f8f..3542b32b540 100644
--- a/mono/metadata/threads.c
+++ b/mono/metadata/threads.c
@@ -77,8 +77,12 @@ mono_native_thread_join_handle (HANDLE thread_handle, gboolean close_handle);
 #include <zircon/syscalls.h>
 #endif
 
-#if defined(HOST_ANDROID) && !defined(TARGET_ARM64) && !defined(TARGET_AMD64)
-#define USE_TKILL_ON_ANDROID 1
+#if defined(HOST_ANDROID) && !(__ANDROID_API__ >= 23) \
+    && ((defined(MIPS) && (CPP_WORDSZ == 32)) \
+        || defined(ARM32) || defined(I386) /* but not x32 */)
+  /* tkill() exists only on arm32/mips(32)/x86. */
+  /* NDK r11+ deprecates tkill() but keeps it for Mono clients. */
+# define USE_TKILL_ON_ANDROID
 #endif
 
 #ifdef HOST_ANDROID
diff --git a/mono/utils/mono-threads-posix.c b/mono/utils/mono-threads-posix.c
index 3e4bf93de5f..79c9f731fe7 100644
--- a/mono/utils/mono-threads-posix.c
+++ b/mono/utils/mono-threads-posix.c
@@ -31,8 +31,12 @@
 
 #include <errno.h>
 
-#if defined(HOST_ANDROID) && !defined(TARGET_ARM64) && !defined(TARGET_AMD64)
-#define USE_TKILL_ON_ANDROID 1
+#if defined(HOST_ANDROID) && !(__ANDROID_API__ >= 23) \
+    && ((defined(MIPS) && (CPP_WORDSZ == 32)) \
+        || defined(ARM32) || defined(I386) /* but not x32 */)
+  /* tkill() exists only on arm32/mips(32)/x86. */
+  /* NDK r11+ deprecates tkill() but keeps it for Mono clients. */
+# define USE_TKILL_ON_ANDROID
 #endif
 
 #ifdef USE_TKILL_ON_ANDROID