diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 459e10a..38784ae 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -27,9 +27,9 @@ on:
 
 env:
   # Use SHA instead of the branch for caching purposes
-  MONO_TAG: mono-6.8.0.123
+  MONO_TAG: mono-6.12.0.111
   PYTHON_VERSION: 3.8
-  EMSDK_VERSION: 1.38.47-upstream
+  EMSDK_VERSION: 1.39.9
   ANDROID_PLATFORM: android-29
   ANDROID_CMAKE_VERSION: 3.6.4111459
   ANDROID_API: 21
diff --git a/files/patches/mono_ios_asl_log_deprecated.diff b/files/patches/mono_ios_asl_log_deprecated.diff
index 7da99bc..11ada2d 100644
--- a/files/patches/mono_ios_asl_log_deprecated.diff
+++ b/files/patches/mono_ios_asl_log_deprecated.diff
@@ -6,8 +6,8 @@ index 3cb127bad59..30ff5edc307 100644
   */
  #include <config.h>
  
--#if defined(HOST_WATCHOS) && (__WATCH_OS_VERSION_MIN_REQUIRED >= __WATCHOS_3_0)
-+#if (defined(HOST_WATCHOS) && (__WATCH_OS_VERSION_MIN_REQUIRED >= __WATCHOS_3_0)) \
+-#if (defined(HOST_WATCHOS) && (__WATCH_OS_VERSION_MIN_REQUIRED >= __WATCHOS_3_0)) || defined(HOST_MACCAT)
++#if (defined(HOST_WATCHOS) && (__WATCH_OS_VERSION_MIN_REQUIRED >= __WATCHOS_3_0)) || defined(HOST_MACCAT) \
 +	|| (defined(HOST_IOS) && (__ENVIRONMENT_IPHONE_OS_VERSION_MIN_REQUIRED__ >= 100000))
  /* emitted by clang:
   *   > /Users/lewurm/work/mono-watch4/mono/utils/mono-log-darwin.c:35:2: error: 'asl_log' is \
diff --git a/format.sh b/format.sh
index 8333cf8..387ddb9 100755
--- a/format.sh
+++ b/format.sh
@@ -6,13 +6,15 @@ IFS=$'\n\t'
 # Loops through all text files tracked by Git.
 git grep -zIl '' |
 while IFS= read -rd '' f; do
-    # Exclude csproj and hdr files.
+    # Exclude csproj and hdr files, and patches.
     if [[ "$f" == *"csproj" ]]; then
         continue
     elif [[ "$f" == *"hdr" ]]; then
         continue
     elif [[ "$f" == *"diff" ]]; then
         continue
+    elif [[ "$f" == *"patch" ]]; then
+        continue
     fi
     # Ensures that files are UTF-8 formatted.
     recode UTF-8 "$f" 2> /dev/null
diff --git a/ios.py b/ios.py
index eb4231a..e1d53de 100755
--- a/ios.py
+++ b/ios.py
@@ -96,6 +96,9 @@ def setup_ios_device_template(env: dict, opts: iOSOpts, target: str):
         'ac_cv_func_futimens=no',
         'ac_cv_func_utimensat=no',
         'ac_cv_func_shm_open_working_with_mmap=no',
+        'ac_cv_func_pthread_jit_write_protect_np=no',
+        'ac_cv_func_preadv=no',
+        'ac_cv_func_pwritev=no',
         'mono_cv_sizeof_sunpath=104',
         'mono_cv_uscore=yes'
     ]
@@ -121,13 +124,7 @@ def setup_ios_device_template(env: dict, opts: iOSOpts, target: str):
     	'-DSMALL_CONFIG', '-D_XOPEN_SOURCE', '-DHOST_IOS', '-DHAVE_LARGE_FILE_SUPPORT=1'
     ]
 
-    LDFLAGS = []
-
-    # https://github.com/mono/mono/issues/19393
-    if os.environ.get('DISABLE_NO_WEAK_IMPORTS', '0') != '1':
-        LDFLAGS += ['-Wl,-no_weak_imports']
-
-    LDFLAGS += [
+    LDFLAGS = [
     	'-arch %s' % arch,
     	'-framework', 'CoreFoundation',
     	'-lobjc', '-lc++'
@@ -225,6 +222,9 @@ def setup_ios_simulator_template(env: dict, opts: iOSOpts, target: str):
         'ac_cv_func_futimens=no',
         'ac_cv_func_utimensat=no',
         'ac_cv_func_shm_open_working_with_mmap=no',
+        'ac_cv_func_pthread_jit_write_protect_np=no',
+        'ac_cv_func_preadv=no',
+        'ac_cv_func_pwritev=no',
         'mono_cv_uscore=yes'
     ]
 
diff --git a/llvm.py b/llvm.py
index a79c759..f7b1cf2 100755
--- a/llvm.py
+++ b/llvm.py
@@ -38,8 +38,8 @@ def make(opts: BaseOpts, target: str):
 
         CMAKE_ARGS += [
             '-DCMAKE_EXE_LINKER_FLAGS="-static"',
-            '-DCROSS_TOOLCHAIN_FLAGS_NATIVE=-DCMAKE_TOOLCHAIN_FILE=%s/external/llvm/cmake/modules/NATIVE.cmake' % opts.mono_source_root,
-            '-DCMAKE_TOOLCHAIN_FILE=%s/external/llvm/cmake/modules/%s.cmake' % (opts.mono_source_root, mxe),
+            '-DCROSS_TOOLCHAIN_FLAGS_NATIVE=-DCMAKE_TOOLCHAIN_FILE=%s/external/llvm-project/llvm/cmake/modules/NATIVE.cmake' % opts.mono_source_root,
+            '-DCMAKE_TOOLCHAIN_FILE=%s/external/llvm-project/llvm/cmake/modules/%s.cmake' % (opts.mono_source_root, mxe),
             '-DLLVM_ENABLE_THREADS=Off',
             '-DLLVM_BUILD_EXECUTION_ENGINE=Off'
         ]
@@ -58,7 +58,7 @@ def make(opts: BaseOpts, target: str):
         replace_in_new_file(
             src_file='%s/sdks/builds/%s.cmake.in' % (opts.mono_source_root, mxe),
             search='@MXE_PATH@', replace=opts.mxe_prefix,
-            dst_file='%s/external/llvm/cmake/modules/%s.cmake' % (opts.mono_source_root, mxe)
+            dst_file='%s/external/llvm-project/llvm/cmake/modules/%s.cmake' % (opts.mono_source_root, mxe)
         )
 
     if target in ['llvm32', 'llvmwin32']:
diff --git a/patch_emscripten.py b/patch_emscripten.py
index 4bccfa5..c3e8947 100755
--- a/patch_emscripten.py
+++ b/patch_emscripten.py
@@ -23,7 +23,6 @@ def main(raw_args):
 
     patches = [
         '%s/sdks/builds/fix-emscripten-8511.diff' % mono_source_root,
-        '%s/sdks/builds/emscripten-pr-8457.diff' % mono_source_root
     ]
 
     from subprocess import Popen